|
|
|
Track 1 |
Case from the practice of Dr Mary Ann K Allison
A 53-year-old woman who, as part of a clinical trial, received dose-dense
AC, nanoparticle albumin-bound
(nab) paclitaxel and tamoxifen
for a 2.2-cm, Grade III, ER-negative, PR-positive, HER2-negative
invasive ductal carcinoma with lymphovascular invasion and 1/16
positive nodes. Within a year, she developed a subpectoral mass.
|
|
Track 2 |
Case from the practice of Dr Frederick M Schnell
A 58-year-old woman who received CMF in 1988 after a modified
radical mastectomy (MRM) for ER-positive, PR-positive, node-negative,
invasive breast cancer. Eleven years later, she underwent excision and
radiation therapy for a contralateral, 0.8-cm, ER-positive, PR-positive,
HER2-negative, node-negative, invasive ductal carcinoma with DCIS. In
2004, she presented with widespread metastatic disease.
|
|
Track 3 |
Case from the practice of Dr Frederick P Smith
A 65-year-old woman treated four years ago for a 1.6-cm, ER-positive,
PR-positive, HER2-negative, node-negative infiltrating
ductal carcinoma. She received tamoxifen for three years, then
began anastrozole, but three months later, a CT revealed hepatic
metastases. |
|
Track 4 |
Case from the practice of Dr Brenda L Towell
A 54-year-old woman treated with mastectomy, dose-dense AC/paclitaxel, radiation therapy and tamoxifen three years ago for a
three-centimeter, ER-positive, PR-negative, HER2-negative breast
tumor with 11 positive nodes. A year later, she was switched to
goserelin and anastrozole because of rising serum tumor markers
and within a few weeks exhibited lymphangitic lung metastases. |
|
Track 5 |
Case from the practice of Dr William G Reeves
A 54-year-old woman who underwent a lumpectomy for a 2.3-cm,
ER-positive, PR-positive, HER2-negative, moderately differentiated
infiltrating ductal carcinoma with negative sentinel nodes and an
Oncotype DX™ score of nine. She has been on anastrozole for the past
2.5 years.
|
|
Track 6 |
Case from the practice of Dr Sara M Garrido
A 53-year-old woman with a history of hypertension and hyper-cholesterolemia
who underwent a lumpectomy for a 0.8-cm, poorly
differentiated, ER-negative, PR-negative, HER2-positive, node-negative,
invasive ductal carcinoma with DCIS. She received six cycles
of TCH followed by trastuzumab for a year. |
|
Track 7 |
Case from the practice of Dr Margaret A Deutsch
A 70-year-old woman who presented with a 1.8-cm, ER-positive,
PR-negative, HER2-positive tumor. Refusing chemotherapy,
she underwent radiation therapy and began anastrozole and
trastuzumab. |
|
Track 8 |
Case from the practice of Dr Atif M Hussein
A 35-year-old woman with a five- to six-centimeter breast mass
consisting of DCIS and high-grade, ER-positive (in 35 percent of
cells), PR-negative (in less than one percent of cells), HER2-negative
invasive tumor. She received four cycles of TAC and underwent
mastectomy. Pathology revealed a 2.7-cm area of DCIS and 14
negative nodes. |
|
Track 9 |
Case from the practice of Dr Stephen A Grabelsky
A 57-year-old woman who underwent a modified radical
mastectomy nine years ago for a 2.6-cm, ER-positive, PR-positive
breast tumor with 2/12 positive nodes, followed by CMF and five
years of tamoxifen. Two years later, she developed a chest wall
recurrence. |
|
Track 10 |
Case from the practice of Dr Deutsch
A 47-year-old woman who presented with a 1.1-cm, triple-negative,
invasive medullary breast cancer. Three years ago, she was treated
with lumpectomy, radiation therapy and tamoxifen for DCIS. The
patient has a strong family history of breast cancer, including her
mother and two aunts. |
|
Track 11 |
Case from the practice of Dr Lowell L Hart
A 37-year-old mother of three who presented in the first trimester
of pregnancy with a four- to five-centimeter, ER-positive, PR-negative,
Grade III, HER2-amplified breast tumor. The pregnancy
was terminated, and she received neoadjuvant TCH. At surgery,
pathology revealed a 0.8-cm area of DCIS with 4/10 positive nodes. |
|
Track 12 |
Case from the practice of Dr Allison
A 44-year-old woman who presented with bilateral axillary
nodes, which were ER-positive, PR-positive, HER2-positive breast
carcinoma. Staging work-up revealed bone and liver metastases. |
|