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Track 1
Case 1 presented to:
Drs Demetri,
Eisenberg and
Trent
Case 2 presented to:
Drs Demetri,
Eisenberg and
Trent

Two cases from the practice of William N Harwin, MD
A 65-year-old woman with a high-risk (11.5 centimeters, >20 mitoses per 50 HPF) gastrointestinal stromal tumor (GIST) in the esophagus who was treated with surgery, radiation therapy and adjuvant imatinib.

A 73-year-old man with a low-risk (three centimeters, ≤2 mitoses per 50 HPF) gastric GIST who was treated with surgery alone.

Track 2
Case 3 presented to:
Drs Demetri, Eisenberg and Trent
Case from the practice of Malek Safa, MD
A 40-year-old woman with a 14-cm gastric GIST (rare mitoses and minimal Ki-67) that was resected. Five years later, the disease recurred in the liver, and she was treated with neoadjuvant and adjuvant imatinib and surgical resection.
Track 3
Case 4 presented to:
Drs Demetri, Eisenberg and Trent
Case from the practice of Lowell Hart, MD
A 51-year-old man with metastatic jejunal GIST that had a KIT exon 9 mutation. The primary GIST was resected, and he received imatinib 800 milligrams daily. His disease eventually progressed in a liver lesion, which was resected, and he remained on imatinib. Sunitinib is now being considered because of disease progression.
Track 4
Case 5 presented to:
Drs Blanke and Rubin

Case from the practice of Daniel J Moriarty, MD
A 58-year-old woman with a 4-cm gastric GIST and mixed large and small cell CD20-positive non-Hodgkin’s lymphoma.
Track 5
Case 6 presented to:
Drs Blanke and Rubin
Case from the practice of John C Leighton Jr, MD
A 64-year-old woman with a 26-cm gastric GIST that was surgically resected and treated with adjuvant imatinib.
Track 6
Case 7 presented to:
Drs Blanke and Rubin
Case from the practice of Joseph F Pizzolato, MD
An 83-year-old woman with a gastric GIST and T3N0 colon cancer. The colon cancer was resected, and imatinib caused a complete response of the GIST.

Track 7
Case 8 presented to:
Drs Blanke and Rubin
Case from the practice of Sushil Bhardwaj, MD
A 78-year-old man with a history of cardiac disease who was treated with increasing doses of imatinib followed by sunitinib for an inoperable 18-cm gastric GIST.

Track 8
Case 9 presented to:
Drs Blanke and Rubin

Case from the practice of Philip T Glynn, MD
A 53-year-old woman with a small bowel GIST who received one year of adjuvant imatinib as part of a randomized clinical trial.
Track 9
Case 10 presented to:
Drs Blanke and Rubin
Case from the practice of Dr Moriarty
A 67-year-old man with a gastric GIST that recurred in the liver. The liver lesions were resected, and he was treated with imatinib.
Track 10
Case 11 presented to: Drs Blanke and
Rubin
Case from the practice of Dr Pizzolato
A 67-year-old woman with a small bowel GIST that recurred. She was treated with imatinib followed by resection. Upon her second recurrence, she was restarted on imatinib.
Track 11
Case 12 presented to:
Drs Blanke and
Rubin
Case from the practice of Dr Glynn
A 47-year-old man with metastatic GIST who was treated with imatinib.
Track 12
Case 13 presented to:
Drs Blanke and
Rubin
Case from the practice of Dr Leighton
A 42-year-old man with a high-risk (10.5 centimeters, 100 mitoses per 50 HPF) gastric GIST that was resected and recurred within one year.