Table of Contents
  CME Information
  Faculty Affiliations; Content Validation and Disclosures;
Medical Oncologist Community Panel
  Editor’s Note:
Figuring it out
Neil Love, MD
   
CASE 1:

A 56-year-old woman with a 1.3-centimeter, high-grade, strongly ER/PRpositive, HER2-positive infiltrating ductal carcinoma with 6/15 positive nodes and extracapsular extension and an ejection fraction of 47 percent but an otherwise unremarkable cardiologic evaluation (from the practice of Dr Mansoor Javeed)
CASE 2:
A 52-year-old woman with a one-centimeter, ER/PR-positive, HER2- negative, node-negative breast cancer who has received three years of adjuvant tamoxifen and became amenorrheic in the past year (from the practice of Dr Edmund W Tai)
CASE 3:
 A 70-year-old woman with painful bony metastases and red-cell transfusion dependence who has been treated with multiple sequential hormonal therapies and zoledronic acid but is reluctant to receive chemotherapy due to concerns about being the sole caretaker of her husband, who has Alzheimer’s disease (from the practice of Dr Joan F Kroener)
CASE 4:
A 66-year-old woman who was diagnosed with lobular carcinoma at age 59 and progressive metastatic disease to the cervical spine one year later, with anemia, bone marrow invasion and skin nodules. The patient experienced a complete clinical remission for approximately 3.5 years while on tamoxifen with subsequent recurrence of bony metastases, skin lesions and pancytopenia (from the practice of Dr Michael A Harris)
CASE 5:
 A 48-year-old woman with a high-grade, five-millimeter, node-negative, ER/PR-negative, HER2-positive ductal carcinoma with extensive DCIS (from the practice of Dr Robert A Moss)
CASE 6:
 A functional 81-year-old woman with hypertension and osteoporosis who lives alone and has a six-centimeter, Grade I, ER/PR-positive, HER2- negative breast cancer with 3/13 positive lymph nodes (from the practice of Dr Michael J Messer)
CASE 7: A 43-year-old woman with a 1.2-centimeter, ER/PR-negative, HER2-positive, node-negative breast cancer treated with adjuvant CMF chemotherapy who two years later developed a skin nodule, a 1.8-centimeter lung mass and rib metastases (from the practice of Dr Helen Collins)
CASE 8: A 61-year-old woman who presented with an ER/PR-positive, nodepositive breast cancer who received AC chemotherapy and tamoxifen and developed bone and lung metastases five years post adjuvant therapy (from the practice of Dr Behrooz Zidehsarai)
CASE 9: A 25-year-old woman with a five-centimeter, ER/PR-positive, HER2-positive breast cancer with a positive sentinel lymph node (from the practice of Dr Edmund W Tai)


2005 VOL 3, ISSUE 4

EDITOR
Neil Love, MD

FACULTY
William J Gradishar, MD
Stephen E Jones, MD
Peter M Ravdin, MD, PhD
Charles L Vogel, MD


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