Meet The Professors: Volume 4, Issue 2
A case-based discussion on the management
of breast cancer in the adjuvant and
metastatic settings


Faculty:
   
Howard A Burris III, MD Peter M Ravdin, MD, PhD  
Daniel F Hayes, MD George W Sledge Jr, MD  


CME INFORMATION

FACULTY AFFILIATIONS AND DISCLOSURES

Case 1: A 58-year-old woman with a two-centimeter, ER/PR-negative, node-negative breast cancer with lymphovascular invasion who refused adjuvant chemotherapy and presented six months later with hepatomegaly, back pain, abnormal liver function tests and imaging that indicated bone and liver metastases (from the practice of Dr Susan L Luedke)

Case 2: A 54-year-old woman with a 1.4-centimeter, moderately differentiated, ER/PR-positive, HER2-negative, node-negative invasive ductal carcinoma (from the practice of Dr Leonard J Seigel)

Case 3: A 57-year-old woman with a six-millimeter, Grade II, ER-positive/PR-negative DCIS who had difficulty tolerating adjuvant tamoxifen (from the practice of Dr Lowell L Hart)

Case 4: A 27-year-old Ashkenazi Jewish woman with a family history of early-age onset breast cancer with a three-centimeter, ER/PR-positive, HER2-positive, node-negative, Grade II invasive ductal carcinoma and extensive DCIS (from the practice of Dr Carolyn B Hendricks)

Case 5: A 56-year-old woman with a three-centimeter, poorly differentiated, ER/PR-negative, HER2-negative breast cancer with 3/16 positive nodes who received dose-dense AC followed by paclitaxel and 16 months later developed visceral metastases (from the practice of Dr David M Dresdner)

Case 6: A very active 67-year-old woman with a 2.2-centimeter, poorly differentiated, ER/PR-positive, HER2-positive infiltrating ductal carcinoma with 4/11 positive nodes (from the practice of Dr Atif M Hussein)

Case 7: An 81-year-old woman with a history of hypertension, diabetes and hyperlipidemia and has ER/PR-positive, HER2-negative breast cancer with two positive lymph nodes (from the practice of Dr Susan L Luedke)

Case 8: A very active 82-year-old woman with an ER-positive breast cancer who refused treatment and three years later presented with a tumor-induced automastectomy with contralateral breast nodules and a lung nodule (from the practice of Dr William G Reeves)

Case 9: A 62-year-old woman who presented with a malignant left pleural effusion and was treated for non-small cell lung cancer and was later determined to have ER/PR-positive, HER2-negative breast cancer (from the practice of Dr William N Harwin)

Case 10: A 53-year-old woman with a strong family history of breast cancer presented with an eight- to 10-centimeter, ER/PR-positive, HER2-positive, poorly differentiated breast cancer with both ductal and lobular features (from the practice of Dr Dennis A Lowenthal)

Case 11: A 39-year-old woman with an ER-positive, PR-negative, HER2-negative breast cancer with 27/27 positive lymph nodes who was treated with dose-dense AC followed by paclitaxel and became amenorrheic. She began receiving tamoxifen 15 months ago and has resumed menses. (from the practice of Dr William N Harwin)