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Meet The Professors: A case-based discussion on the management of breast cancer in the adjuvant and metastatic settings

OVERVIEW OF ACTIVITY

Breast cancer is one of the most rapidly evolving fields in medical oncology. Published results from ongoing clinical trials lead to the continuous emergence of new therapeutic agents and changes in the indications for existing treatments. To offer optimal patient care — including the option of clinical trial participation — practicing medical oncologists, hematologists and hematology-oncology fellows must be well informed of these advances. Meet The Professors uses relevant case-based discussions between community oncologists and clinical investigators to help practicing clinicians incorporate this information into their management strategies for breast cancer.

LEARNING OBJECTIVES

• Incorporate the use of validated biomarkers and genomic assays in the quantification of disease risk and the selection of appropriate treatment for breast cancer.
• Compare and contrast the safety and efficacy of anthracycline- and nonanthracycline-containing adjuvant regimens when recommending chemotherapy for patients with early breast cancer.
• Devise an algorithm for the endocrine treatment of pre- and postmenopausal women with ER-positive early breast cancer, addressing total duration of therapy, management of side effects and the evolving role of bisphosphonates.
• Recommend treatment strategies for HER2-positive early and advanced breast cancer, considering the utility of trastuzumab for small, node-negative tumors in addition to the individualized and sequential use of chemobiologic regimens.
• Recognize the risks and benefits of the first-line use of bevacizumab for HER2-negative metastatic breast cancer.
• Counsel appropriately selected patients with breast cancer about participation in ongoing clinical trials.
• Assess the effectiveness of personal strategies for preventing emotional and physical “burnout” in the practice of oncology.

ACCREDITATION STATEMENT

Research To Practice is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

CREDIT DESIGNATION STATEMENT

Research To Practice designates this educational activity for a maximum of 2.75 AMA PRA Category 1 Credits™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

HOW TO USE THIS CME ACTIVITY

This CME activity contains an audio component. To receive credit, the participant should review the CME information, listen to the CDs and complete the Educational Assessment and Credit Form located on our website at MeetTheProfessors.com.

This program is supported by educational grants from Abraxis BioScience, AstraZeneca Pharmaceuticals LP, Genentech BioOncology and Genomic Health Inc.